Medchemexpress LLC O-Propargyl-Puromycin | 1416561-90-4 | 98.4% | 495.53 | 50 MG

Supplier:  Medchemexpress LLC 50MGHY15680

O-Propargyl-Puromycin is a potent protein synthesis inhibitor and an alkyne analog of puromycin. It functions as a click chemistry reagent, featuring an Alkyne group that can engage in copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

• Protein synthesis inhibition: It effectively inhibits protein synthesis in both reticulocyte lysates and cultured cells.
• Covalent conjugates: This compound forms covalent conjugates with nascent polypeptide chains.
• Rapid turnover: These conjugates are rapidly turned over by the proteasome.
• Visualization and capture: The covalent conjugates can be visualized or captured through copper(I)-catalyzed azide-alkyne cycloaddition.
• Imaging and affinity purification: It can be utilized to image and affinity-purify nascent proteins within cells and animals.

Catalog No. 50-003-64269