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Medchemexpress LLC OARV-771 | 2683008-37-7 | 98.8% | C49H59ClN8O8S2 | 50 MG
Supplier: Medchemexpress LLC HY14526450MG
OARV-771 is a VHL-based BET degrader (PROTAC) with improved cell permeability. It demonstrates DC50 values of 6 nM for Brd4, 1 nM for Brd2, and 4 nM for Brd3, and shows an antiproliferative effect with an EC50 value of 4 nM in MV4;11 cells.
- VHL-based BET degrader (PROTAC)
- Improved cell permeability
- DC50 for Brd4: 6 nM
- DC50 for Brd2: 1 nM
- DC50 for Brd3: 4 nM
- Antiproliferative effect with EC50 of 4 nM in MV4;11 cells
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