Oasis PRiME MCX is a highly efficient, orthogonal (reversed-phase and ion-exchange) solid-phase extraction product based on MCX technology. It is designed for targeted cleanup of basic compounds with pKa ≥ 4.5. The methods are patent pending.
- Utilizes a defined, generic 3- or 4-step SPE protocol based on the water-wettable strong cation-exchange/reversed-phase sorbent, eliminating the need for extensive method development. No conditioning and equilibration steps are required.
- Simpler methods remove up to 99% of phospholipids, which are a major cause of matrix effects, ion suppression, shorter column lifetimes, increased MS maintenance, and higher variability in LC-MS quantification. It is QC tested for phospholipid removal.
- Cartridges and plates are designed with a manufacturing optimization to increase flow reproducibility across devices, making processing time more predictable.