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Cayman Chemical OchratoxIn A-13C20 1.2mL
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Supplier:  Cayman Chemical 312951.2 ML

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A neurosteroid and positive allosteric modulator of GABAA receptors inhibits binding of TBPS and increases binding of flunitrazepam to rat synaptosomal membrane preparations in a concentration-dependent manner potentiates GABA-induced chloride currents in cultured rat hippocampal and spinal cord neurons inhibits seizures induced by pilocarpine or PTZ in mice (ED50s 7 3 and 15 mg/kg respectively) increases the number of entries into and percentage of time spent in the open arms of the elevated plus maze in mice at 20 mg/kg

Catalog No. 50-299-1851


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