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Promab Oct-4 mRNA-LNP, 200uL, mRNA-LNPs suspended in PBS (-Ca, -Mg) (pH: 7.0-7.4).
Supplier: Promab PMLNP0042
OCT-4 (Octamer-binding transcription factor 4) is a transcription factor protein of the POU (Pit-Oct-Unc) family, encoded by the POU5F1 gene. The transcription factor Oct-4 is capable of inducing an embryonic stem cell-like state, and it works together with Sox2, Klf4, and usually c-Myc to generate induced pluripotent stem cells (iPSCs). These factors are commonly referred to as "Yamanaka reprogramming factors," and this reprogramming effect reverts human fibroblasts to iPSCs. In addition, Oct-4 plays a crucial role in determining the fate of endoplasmic cells and embryonic stem cells, with the function of maintaining the pluripotency of embryonic cells or regulating the proliferation of cancer cells. This product is designed as a tool for the delivery and expression of OCT-4 mRNA for research.
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