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Medchemexpress LLC Octaarginine acetate | 98.3% | 1267.50 | 5 MG
Supplier: Medchemexpress LLC HYP2483B5MG
Octaarginine acetate is a cell-penetrating peptide and proteasome inhibitor. It exhibits mixed-type inhibition against 20S proteasome chymotrypsin-like, caspase-like, and trypsin-like activities, and inhibits 26S proteasome activity with decreased efficiency. It induces ubiquitin-conjugated protein accumulation, mediates HSPG-dependent cellular internalization via macropinocytosis, and enhances liposomal cargo uptake and gene delivery. Octaarginine acetate can be used for the research of cervix carcinoma, collagen antibody-induced arthritis, and bacterial infections.
- Potently inhibits chymotrypsin-like and caspase-like activities of 20S proteasomes.
- Efficiently delivers protein, peptide, and plasmid DNA cargos into cultured cells.
- Inhibits the growth of E. coli and S. aureus bacterial cells.
- Inhibits HeLa human cancer cell growth in a concentration-dependent manner.
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