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Cayman Chemical OctahydrocurcumIn 10mg
Supplier: Cayman Chemical 3368610 MG
A VCP modulator inhibits VCP ATPase activity (IC50 330 nM) inhibits tunicamycin-induced cell death ATP depletion and upregulation of CHOP in HeLa cells at 20 50 and 50 M respectively inhibits OGD-induced ATP depletion and cell death in rat primary cortical neurons in an in vitro model of cerebral ischemia at 100 M reduces infarction volume and increases the latency to fall in an accelerating rotarod test in a mouse model of focal cerebral ischemia induced by transient distal MCAO at 100 mg/kg immediately following occlusion and again at 50 mg/kg following reperfusion inhibits thinning of the retinal outer nuclear layer and preserves visual function in an rd10 mouse model of retinitis pigmentosa at 50 mg/kg
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