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Cayman Chemical OctreotIdeacetate 10mg
Supplier: Cayman Chemical 2375710 MG
A somatostatin receptor agonist (Kis = 875, 0.57, 26.8, >1,000, and 6.8 nM for SST1-5 receptors, respectively); selectively binds to SST2 over SST3 and SST5 receptors (IC50s = 0.02, 92.9, and 21.8 nM, respectively); inhibits the secretion of growth hormone in vitro in rat pituitary cells three-fold more potently than somatostatin; inhibits the secretion of growth hormone in vivo in rhesus monkey (ID50 = 0.38 UG/kg per hour); inhibits proliferation of VEGF-stimulated human umbilical endothelial cells (HUVECs) with an EC50 value of approximately 1 µM; inhibits growth of LCI-D20 human hepatocellular carcinoma cell tumors in a nude mouse xenograft model when administered at a dose of 50 UG/kg twice daily
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