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Medchemexpress LLC Odanacatib | 603139-19-1 | 99.8% | 525.56 | 250 MG
SDP

Supplier:  Medchemexpress LLC 250MGHY10042

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Odanacatib is a potent and selective inhibitor of cathepsin K, demonstrating an IC50 of 0.2 nM for human cathepsin K. This compound is intended for research use only and exhibits weak inhibition of antigen presentation and MHC II invariant chain protein processing.

  • Reduces resorption activity.
  • Accumulates labeled degraded bone matrix proteins in cathepsin K containing vesicles.
  • Suppresses bone resorption markers and serum bone formation markers in OVX monkeys.
  • Increases periosteal bone formation and cortical thickness.
  • Enhances bone volume/total volume and bone mineral density in OVX models.

Catalog No. 50-003-47597


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