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Medchemexpress LLC ODN 2007 sodium | 455348-63-7 | [DNA, d(P-thio)(T-C-G-T-C-G-T-T-G-T-C-G-T-T-T-T-G-T-C-G-T-T), sodium salt] | 1 MG

Supplier: Medchemexpress LLC HY150734A1MG
ODN 2007 sodium is a class B CpG oligodeoxynucleotide (ODN) and a Toll-like receptor (TLR) ligand. It functions as an immunomodulator and vaccine adjuvant, enhancing immune responses in mammals, fish, and humans. The sequence is 5'-TCGTCGTTGTCGTTTTGTCGTT-3'.
- Purity of 99.69%
- Appears as a solid
- Color is white to off-white
- Enhances immune responses
- Functions as an immunomodulator
- Acts as a vaccine adjuvant
- TLR ligand
- Induces chicken macrophage interferon IFN-γ and IFN-β expression in vitro
- Increases phosphorylation of ERK2 and AKT, and stimulates NO production in vitro
- Enhances immune response in zebrafish against Vibrio traumaticus infection in vivo
- Reduces cumulative mortality rate in treated zebrafish group in vivo
- Decreases expression levels of intestinal immune-related genes in vivo
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