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Enzo Life Sciences ODQ (50mg). CAS: 41443-28-1
SDP

Supplier:  Enzo Life Sciences ALX270034M050

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Guanylyl cyclase inhibitor. ODQ is a potent and selective, direct-acting inhibitor of guanylate cyclase (IC50=20 nM). In cerebellar slices ODQ reversibly inhibited cGMP generation in response to endogenous NO or exogenously added NO-donors. ODQ does not inhibit NO-mediated macrophage toxicity (a phenomenon unrelated to cGMP) and does not inhibit particulate guanylyl cyclase or adenylyl cyclase. ODQ is an unique and selective tool to elucidate the physiological importance of the NO-cGMP pathway. Formula: C9H5N3O2. MW: 187.2. Purity: ≥98% (TLC). Appearance: Off-white to yellow powder. Solubility: Soluble in DMSO (5mg/ml), ethyl acetate or 100% ethanol (1.2mg/ml); insoluble in water. Use/Stability: Solutions may decompose slowly. Long Term Storage: -20°C. Handling: Protect from light.

Catalog No. 50-200-8374


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