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Medchemexpress LLC OF-02 | 1883431-67-1 | ≥98.0% | C84H152N4O6 | 25 MG
Supplier: Medchemexpress LLC 25MGHY145795
OF-02 is an ionizable lipid essential for mRNA delivery, serving as a key component of lipid nanoparticles (LNPs). It becomes protonated in acidic endosomal environments, which aids in the escape of mRNA and effective protein expression in target cells. The lipid's pH-responsive membrane fusion properties allow it to complex with mRNA, disrupt endosomal membrane structures, and facilitate mRNA release into the cytoplasm.
- Ionizable lipid for mRNA delivery
- Key component of lipid nanoparticles (LNPs)
- Promotes endosomal escape of mRNA
- Induces protein expression in target cells
- Utilizes pH-responsive membrane fusion properties
- Enables mRNA release into the cytoplasm
- Used in mRNA vaccine development
- Used in gene editing applications
- Used in protein replacement therapy
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