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Apexbio Technology LLC Ofloxacin 82419-36-1 1g
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Catalog No. 5000097202
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Ofloxacin (CAS 82419-36-1) is a small-molecule inhibitor targeting bacterial DNA gyrase (topoisomerase II) and topoisomerase IV It is designed to inhibit these enzymes thereby blocking bacterial DNA replication and transcription Ofloxacin exerts its biological activity primarily through disruption of DNA supercoiling by binding to the enzyme-DNA complex preventing proper DNA synthesis and bacterial proliferation In in vitro studies ofloxacin demonstrates inhibitory activity with reported IC50 values ranging from 0 5 to 10 g/mL depending on bacterial strain variability and experimental conditions Based on these pharmacological properties ofloxacin holds research potential in microbiological and pharmaceutical studies such as bacterial resistance research evaluation of bacterial enzyme inhibition susceptibility assay validation and investigation of bacterial gene regulation and replication mechanisms

Catalog No. 50-000-97202 Supplier Apexbio Technology LLC Supplier No. A55111000
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Ofloxacin (CAS 82419-36-1) is a small-molecule inhibitor targeting bacterial DNA gyrase (topoisomerase II) and topoisomerase IV It is designed to inhibit these enzymes thereby blocking bacterial DNA replication and transcription Ofloxacin exerts its biological activity primarily through disruption of DNA supercoiling by binding to the enzyme-DNA complex preventing proper DNA synthesis and bacterial proliferation In in vitro studies ofloxacin demonstrates inhibitory activity with reported IC50 values ranging from 0 5 to 10 g/mL depending on bacterial strain variability and experimental conditions Based on these pharmacological properties ofloxacin holds research potential in microbiological and pharmaceutical studies such as bacterial resistance research evaluation of bacterial enzyme inhibition susceptibility assay validation and investigation of bacterial gene regulation and replication mechanisms

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