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AdipoGen Oleacein
Supplier: AdipoGen AGCN20535M005
Chemical. CAS 149183-75-5. Formula C17H20O6. MW 320.3. Oleacin is a phenolic compound of extra virgin olive oil and has antioxidant, anti-inflammatory, antitumor, antiproliferative, antimicrobial, cardioprotective, antiobesity and antiatherosclerotic properties. In vitro studies showed that oleacein reduces ROS production by f-MLP and PMA-stimulated neutrophils inhibiting the release of myeloperoxidase. 5-Lipoxygenase 5-LOX and NF-kappaB signaling inhibitor. Improves insulin sensitivity in obese mice. Dual substrate-inhibitor of catechol-O-methyltransferase. Inhibits the catalytic activities of nicotinamide N-methyltransferase, ATP-citrate lyase, lysine-specific demethylase 6A and N-methyltransferase 4.
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