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Medchemexpress LLC Oleanolic acid 28-O-β-D-glucopyranoside | 14162-53-9 | 5 MG
Supplier: Medchemexpress LLC HYN76355MG
Oleanolic acid 28-O-β-D-glucopyranoside is an orally active pentacyclic triterpenoid compound with anti-inflammatory effects. It inhibits inflammatory responses, enhances intestinal epithelial barrier function, and modulates gut microbiota in ulcerative colitis models. Its mechanism of action is related to the PI3K-AKT and MAPK signaling pathways and can be used in research for diseases such as colitis.
- Orally active pentacyclic triterpenoid compound with anti-inflammatory effects
- Inhibits inflammatory responses and modulates gut microbiota
- Enhances intestinal epithelial barrier function
- Targets IL-6 and COX-2 pathways
- Increases transepithelial electrical resistance (TEER) and tight junction protein expression in Caco-2 cells
- Reduces inflammatory cytokines (IL-6, TNF-α, COX-2, iNOS) in Caco-2 cells
- Ameliorates ulcerative colitis in mouse models by reducing inflammation and improving colon health
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