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Medchemexpress LLC Oleanolic acid | 508-02-1 | 98.0% | 456.70 | 100 MG
Supplier: Medchemexpress LLC 100MGHYN0156
Oleanolic acid is a natural compound found in plants known for its anti-tumor activities. It targets autophagy, endogenous metabolites, HIV, and MAP3K, impacting pathways related to autophagy, metabolic enzymes, anti-infection, and MAPK/ERK.
- Suppresses proliferation of lung cancer cells
- Increases miR-122 abundance
- Induces autophagy in normal tissue-derived cells without cytotoxicity
- Impairs invasion and anchorage-independent growth of KRAS-transformed normal cells
- Suppresses tumor xenograft growth by inducing autophagy
- Triggers activation of MAPK pathways (p-38 MAPK, JNK, and ERK)
- Induces reactive oxygen species-dependent ASK1 activation for p38 MAPK-dependent apoptosis
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