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Medchemexpress LLC Oligodeoxynucleotide ODN 2216 (CpG oligodeoxynucleotide) | 332437-00-0 | 97.9% | 6,432.00 Da | 10 MG
SDP

Catalog No. 5000286870
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ODN 2216 is a Class A CpG oligodeoxynucleotide that acts as a human-specific Toll-like receptor 9 (TLR9) ligand and research reagent. It elicits robust type I interferon responses from plasmacytoid dendritic cells, promotes dendritic cell cytokine production, and can indirectly stimulate IFN-γ production in peripheral blood mononuclear cells.

  • Human-specific TLR9 agonist that induces type I interferons.
  • Stimulates IFN-α and IFN-β production by plasmacytoid dendritic cells.
  • Promotes IL-12 production by dendritic cells and indirect IFN-γ production in PBMCs.
  • Sequence: d(G-sp-G-sp-G-G-G-A-C-G-A-T-C-G-T-C-G-sp-G-sp-G-sp-G-sp-G-sp-G).
  • Molecular weight approximately 6,432 Da and purity ~97.9%.
  • Supplied as a 10 mg package; store sealed and away from moisture (in solvent: -80°C up to 6 months, -20°C up to 1 month).

Catalog No. 50-002-86870 Supplier Medchemexpress LLC Supplier No. HY15074110MG
May include imposed supplier surcharges.
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ODN 2216 is a Class A CpG oligodeoxynucleotide that acts as a human-specific Toll-like receptor 9 (TLR9) ligand and research reagent. It elicits robust type I interferon responses from plasmacytoid dendritic cells, promotes dendritic cell cytokine production, and can indirectly stimulate IFN-γ production in peripheral blood mononuclear cells.

  • Human-specific TLR9 agonist that induces type I interferons.
  • Stimulates IFN-α and IFN-β production by plasmacytoid dendritic cells.
  • Promotes IL-12 production by dendritic cells and indirect IFN-γ production in PBMCs.
  • Sequence: d(G-sp-G-sp-G-G-G-A-C-G-A-T-C-G-T-C-G-sp-G-sp-G-sp-G-sp-G-sp-G).
  • Molecular weight approximately 6,432 Da and purity ~97.9%.
  • Supplied as a 10 mg package; store sealed and away from moisture (in solvent: -80°C up to 6 months, -20°C up to 1 month).

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