Medchemexpress LLC Oligodeoxynucleotide ODN 2216 (CpG oligodeoxynucleotide) | 332437-00-0 | 97.9% | 6,432.00 Da | 10 MG

Supplier:  Medchemexpress LLC HY15074110MG

ODN 2216 is a Class A CpG oligodeoxynucleotide that acts as a human-specific Toll-like receptor 9 (TLR9) ligand and research reagent. It elicits robust type I interferon responses from plasmacytoid dendritic cells, promotes dendritic cell cytokine production, and can indirectly stimulate IFN-γ production in peripheral blood mononuclear cells.

• Human-specific TLR9 agonist that induces type I interferons.
• Stimulates IFN-α and IFN-β production by plasmacytoid dendritic cells.
• Promotes IL-12 production by dendritic cells and indirect IFN-γ production in PBMCs.
• Sequence: d(G-sp-G-sp-G-G-G-A-C-G-A-T-C-G-T-C-G-sp-G-sp-G-sp-G-sp-G-sp-G).
• Molecular weight approximately 6,432 Da and purity ~97.9%.
• Supplied as a 10 mg package; store sealed and away from moisture (in solvent: -80°C up to 6 months, -20°C up to 1 month).

Catalog No. 50-002-86870