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AdipoGen Oligomycin A
SDP

Supplier:  AdipoGen AGCN20517M001

Encompass_Preferred

Chemical. CAS 579-13-5. Formula C45H74O11. MW 791.1. Synthetic. Originally isolated from Streptomyces diastatochromogenes. Potent mitochondrial ATP synthase ATPases F1F0 inhibitor, consequently leading to inhibition of oxidative phosphorylation OXPHOS. Useful agent for immunometabolism research. Inhibits ATP synthase by blocking its proton channel F0 subunit, which is necessary for oxidative phosphorylation of ADP to ATP energy production, significantly reducing electron flow through the electron transport chain. Anticancer agent. Shown to induce apoptosis/necroptosis in a variety of cell types, as well as autophagy. Shown to activate AMPK. Broad antifungal, antibiotic and nematocidal agent.

Catalog No. 50-256-2500


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