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Medchemexpress LLC Olodaterol | 868049-49-4 | 99.85% | C21H26N2O5 | 100 MG
SDP

Supplier:  Medchemexpress LLC HY14301100MG

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Olodaterol is a selective, long-acting β2-adrenoceptor (β2-AR) agonist with an EC50 of 0.1 nM and pKi of 9.14 for human β2-adrenoceptor. It is used for chronic obstructive pulmonary disease (COPD) and pulmonary fibrosis. It is intended for research use only.

  • Selective, long-acting β2-adrenoceptor agonist
  • Attenuates growth factor-induced motility and proliferation in fibroblasts
  • Interferes with FGF-induced phosphorylation of signaling cascades
  • Increases intracellular cAMP in fibroblasts
  • Inhibits PICP increase in fibroblasts
  • Accelerates body weight recovery and attenuates TGF-β-induced lung fibrosis in mice
  • Induces dose-dependent bronchoprotection in guinea pigs and dogs

Catalog No. 50-003-54830


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