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Medchemexpress LLC Olprinone hydrochloride | 119615-63-3 | 99.9% | C14H11ClN4O | 50 MG
Supplier: Medchemexpress LLC HY1425450MG
Olprinone Hydrochloride is a potent phosphodiesterase (PDE) 3 inhibitor, showing IC50s of 0.35 μM for PDE3. It is utilized in research for heart failure due to its positive inotropic and vasodilative effects, and also demonstrates anti-inflammatory activity.
- Potent PDE3 inhibitor
- Used in research for heart failure
- Exhibits positive inotropic and vasodilative effects
- Demonstrates anti-inflammatory activity
- Modulates inflammation associated with myocardial ischemia-reperfusion injury
- Reduces pro-inflammatory cytokines such as TNF-α and IL-1β
- Decreases expression of adhesion molecules like ICAM-1 and P-Selectin
- Inhibits apoptosis related to myocardial injury
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