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Medchemexpress LLC Ombrabulin hydrochloride | 253426-24-3 | 99.4% | 438.90 | 100 MG
Supplier: Medchemexpress LLC HY18256100MG
Ombrabulin hydrochloride is a derivative of CA-4 phosphate, known to exhibit antivascular effects through selective disruption of the tubulin cytoskeleton of endothelial cells. It acts as a tubulin inhibitor, demonstrating potent cytotoxicity against various cancer cell lines and showing efficacy in reducing tumor weight in vivo.
- Acts as a tubulin inhibitor
- Exhibits antivascular effects
- Disrupts the tubulin cytoskeleton of endothelial cells
- Shows cytotoxicity against DU-145, HeLa, MCF7, NCI-H460, and SK-OV-3 cell lines
- Proven effective in reducing tumor weight in animal models
- Tested in clinical trials for solid tumors and various cancers
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