Cayman Chemical Omeprazole sulfIde-d3 1mg

Supplier:  Cayman Chemical 402601 MG

A pre-mRNA splicing modulator corrects aberrant splicing in a SPREADD using HeLa cells expressing IKBKAP with an IVS20 6TC point mutation restores the modification of cytoplasmic tRNAs with uridine in the wobble position in primary human fibroblasts from patients with FD to the same level as in primary human fibroblasts from carriers of the FD mutation at 2 UM increases the levels of correctly spliced PARK7 mRNA in neural precursor cells differentiated from fibroblasts of patients with the homozygous PARK7 c.192GC exonic splicing mutation in combination with phenylbutyric acid intratumoral administration decreases tumor volume and increases survival and the number of tumor-infiltrating CD8 T cells in an MC-38 murine colon carcinoma model

Catalog No. 50-294-4105