Cayman Chemical Omeprazole sulfIde-d3 5mg

Supplier:  Cayman Chemical 402605 MG

A chalcone derivative and an inhibitor of the MD-2-LPS interaction inhibits the interaction between MD-2 and LPS in a cell-free assay at 0.1 UM inhibits LPS-induced increases in the levels of Tnf-a and Il-6 secreted from isolated and washed MPMs (IC50s 4.27 and 2.09 UM respectively) inhibits LPS-induced Nf-KB DNA binding in MPMs at 5 and 20 UM inhibits the growth of various cancer cells (GI50s 0.019-0.32 UM respectively) reduces tumor volume and weight in a HeLa cervical mouse xenograft model at 10 mg/kg for three days prevents LPS-induced increases in BALF total protein levels and CD68 macrophage and neutrophil infiltration in a mouse model of LPS-induced acute lung injury at 20 mg/kg per day reduces MPO activity in isolated neutrophils in the same model

Catalog No. 50-294-5797