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TARGETMOL CHEMICALS INC ON-01910 25MG

Supplier: TARGETMOL CHEMICALS INC T607025MG
Also available in 2 mg 5 mg 10 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. ON-01910 is a non-ATP-competitive PLK1 inhibitor(IC50 of 9 nM in a cell-free assay). It shows 30-fold greater selectivity against Plk2 and no activity to Plk3. Rigosertib inhibits PI3K/Akt pathway and activates oxidative stress signals. Rigosertib induces apoptosis in various cancer cells.It is a synthetic benzyl styryl sulfone analogue with potential antineoplastic activity. purity: 99%
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