Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
Learn More
Cayman Chemical on-8711dIcyclohexylamIn s 10mg
Supplier: Cayman Chemical 3843210 MG
An EP1 receptor antagonist (Kis = 0.6 and 1.7 nM for human and mouse receptors, respectively, expressed in CHO cells); is selective for EP1 over EP2, EP3, and EP4 (Kis = >1,000, 67, and >1,000 nM, respectively, for mouse receptors expressed in CHO cells); inhibits PGE2-induced increases in intracellular calcium concentrations in cells expressing human or mouse EP1 (EC50s = 50 and 210 nM, respectively); reduces the incidence of squamous cell carcinoma and severe dysplasia induced by 4-nitroquinoline 1-oxide in a rat model of tongue carcinogenesis at 400 and 800 ppm in the diet
Product Title
By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.
Spot an opportunity for improvement?