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Medchemexpress LLC Oncrasin-1 | 75629-57-1 | 98.2% | 269.73 | 100 MG
Supplier: Medchemexpress LLC HY16662100MG
Oncrasin-1 is an RNA polymerase inhibitor that suppresses the phosphorylation of RNA polymerase II and the expression of intronless reporter genes in sensitive cells. It effectively kills various human lung cancer cells with K-Ras mutations. It leads to coaggregation of PKCι and splicing factors into megaspliceosomes, inducing malfunction in the RNA processing machinery. This anti-cancer agent can be studied in research for lung cancer.
- RNA polymerase inhibitor
- Suppresses phosphorylation of RNA polymerase II and expression of intronless reporter genes
- Effectively kills human lung cancer cells with K-Ras mutations
- Induces coaggregation of PKCι and splicing factors into megaspliceosomes
- Causes malfunction in the RNA processing machinery
- Anti-cancer agent for lung cancer research
- Appears as a light yellow to khaki solid
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