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Medchemexpress LLC Ondansetron hydrochloride | 99614-01-4 | MFCD00764297 | 99.4% | C18H20ClN3O | 100 MG
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Supplier:  Medchemexpress LLC HYB0002100MG

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Ondansetron hydrochloride (GR 38032; SN 307) is a highly selective 5-HT3 receptor antagonist. It exerts its antiemetic effect by antagonizing 5-HT receptors in the peripheral and central nervous systems, inhibiting nausea and vomiting induced by chemotherapy and radiotherapy.

  • Highly selective 5-HT3 receptor antagonist (IC50: 103 pM)
  • Exerts antiemetic effect
  • Inhibits nausea and vomiting from chemotherapy and radiotherapy
  • Reduces EAAT3 response to L-glutamate (IC50: 8.57 μM)
  • Exhibits anti-inflammatory effects through 5-HT3 receptor

Catalog No. 50-004-32227


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