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Medchemexpress LLC ONO-2952 | 895169-20-7 | 99.5% | 398.86 | 50 MG
SDP

Catalog No. 5000343684
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ONO-2952 is a potent, selective, and orally active antagonist of translocator protein 18 kDa (TSPO), exhibiting a Ki range of 0.33-9.30 nM for both rat and human TSPO. It demonstrates greater selectivity for TSPO compared to other receptors, transporters, ion channels, and enzymes. This compound achieves anti-stress effects by inhibiting the excessive activation of the noradrenergic system in the brain, without inducing amnesic effects. ONO-2952 shows potential for the treatment of irritable bowel syndrome.

  • Potent, selective and orally active.
  • More selective for TSPO than other receptors, transporters, ion channels and enzymes.
  • Exerts anti-stress effects through inhibition of excessive activation of noradrenergic system in the brain.
  • Does not cause amnesic effects.
  • Has potential for irritable bowel syndrome treatment.

Catalog No. 50-003-43684 Supplier Medchemexpress LLC Supplier No. HY11119150MG
May include imposed supplier surcharges.
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ONO-2952 is a potent, selective, and orally active antagonist of translocator protein 18 kDa (TSPO), exhibiting a Ki range of 0.33-9.30 nM for both rat and human TSPO. It demonstrates greater selectivity for TSPO compared to other receptors, transporters, ion channels, and enzymes. This compound achieves anti-stress effects by inhibiting the excessive activation of the noradrenergic system in the brain, without inducing amnesic effects. ONO-2952 shows potential for the treatment of irritable bowel syndrome.

  • Potent, selective and orally active.
  • More selective for TSPO than other receptors, transporters, ion channels and enzymes.
  • Exerts anti-stress effects through inhibition of excessive activation of noradrenergic system in the brain.
  • Does not cause amnesic effects.
  • Has potential for irritable bowel syndrome treatment.

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