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Medchemexpress LLC Ontunisertib (AGMB-129) | 2647949-48-0 | 99.95% | 469.49 | 5 MG
SDP

Catalog No. 5000390869
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Ontunisertib (AGMB-129) is an orally active and selective gastrointestinal-restricted ALK5 (TGFβR1) inhibitor. It blocks signaling of the pro-fibrotic TGFβ pathway and can be used for the research of fibrostenotic Crohn's disease.

  • Orally active and selective gastrointestinal-restricted ALK5 (TGFβR1) inhibitor.
  • Blocks signaling of the pro-fibrotic TGFβ pathway.
  • Can be used for the research of fibrostenotic Crohn's disease.
  • Designed to act locally in the gastrointestinal tract, enabling high exposure in the target tissue.
  • Rapidly inactivated in the liver following absorption to avoid potential toxicities associated with systemic TGFβ signaling inhibition.

Catalog No. 50-003-90869 Supplier Medchemexpress LLC Supplier No. HY1689905MG
May include imposed supplier surcharges.
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Ontunisertib (AGMB-129) is an orally active and selective gastrointestinal-restricted ALK5 (TGFβR1) inhibitor. It blocks signaling of the pro-fibrotic TGFβ pathway and can be used for the research of fibrostenotic Crohn's disease.

  • Orally active and selective gastrointestinal-restricted ALK5 (TGFβR1) inhibitor.
  • Blocks signaling of the pro-fibrotic TGFβ pathway.
  • Can be used for the research of fibrostenotic Crohn's disease.
  • Designed to act locally in the gastrointestinal tract, enabling high exposure in the target tissue.
  • Rapidly inactivated in the liver following absorption to avoid potential toxicities associated with systemic TGFβ signaling inhibition.

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