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Cayman Chemical Ophopogons radx Ruscogen 10mg
Supplier: Cayman Chemical 2521710 MG
A steroid sapogenin with diverse biological activities; reduces PMA-induced adhesion of HL-60 cells to ECV304 cells (IC50 = 7.76 nM); decreases zymosan A-induced peritoneal leukocyte migration in rats at 5 mg/kg; inhibits ADP-induced platelet aggregation in rats at 12.5 mg/kg; prevents monocrotaline-induced increases in MAP, expression of IL-1β and TNF in plasma and lung, and endothelial cell apoptosis in pulmonary arterioles in a rat model of pulmonary hypertension; reduces proteinuria and renal macrophage infiltration in a rat model of streptozotocin-induced diabetes; decreases gene expression of inflammatory cytokines, dyslipidemia, and liver steatosis in a hamster model of high-fat diet-induced NASH
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