AdipoGen Oregon Green 488 DA

Supplier:  AdipoGen CDXD0150M100

Chemical. CAS 1027558-93-5. Formula C24H14F2O7. MW 452.4. 2,7-Difluorofluorescein, also called Oregon Green 488 OG488 dye is a bright, green-fluorescent dye with excitation ideally suited to the 488 nm laser line and useful for fluorescent labeling. It has a high extinction coefficient and fluorescence quantum yield and while it is pH insensitive in the physiological range, with a pKa of 4.6 it can be used to as a fluorescent indicator for intracellular pH and monitor pH changes in acidic organelles or pathways. OG488 is a fluorinated analog of fluoresceins. The absorption and emission spectra of OG488 perfectly match those of fluorescein. Because of the near match of the absorption maxima on proteins ~498 nm and ~512 nm to the strong 488 nm and 514 nm spectral lines of the argon-ion laser, the Oregon Green 488 fluorphore is an important dye for both confocal laser-scanning microscopy and flow cytometry applications.

Catalog No. 50-256-1212