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Apexbio Technology LLC Orexin A (human, rat, mouse)(Synonyms: Hypocretin-1, Hcrt-1, Orexin-A, Orexin 1, Hypocretin 1 (human, rat, mouse), OXA), 500ug, CAS: 205640-90-0.
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Catalog No. 5000061061
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Orexin A (human, rat, mouse; CAS 205640-90-0) is a hypothalamic neuropeptide composed of 33 amino acids, functioning as an endogenous agonist at orexin-1 and orexin-2 receptors. Binding to these G-protein coupled receptors, orexin A regulates multiple physiological processes including appetite, arousal states, locomotion, hypothalamic-pituitary-adrenal axis activity, and pain perception thresholds. Preclinical studies have demonstrated that intravenous administration of orexin A (3–30 mg/kg) significantly increases paw withdrawal latency in thermal nociception assays, suggestive of analgesic potential. Hence, orexin A serves as a useful tool for investigating neuroendocrine control mechanisms and corresponding therapeutic targets.

Catalog No. 50-000-61061 Supplier Apexbio Technology LLC Supplier No. B51170.5
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Orexin A (human, rat, mouse; CAS 205640-90-0) is a hypothalamic neuropeptide composed of 33 amino acids, functioning as an endogenous agonist at orexin-1 and orexin-2 receptors. Binding to these G-protein coupled receptors, orexin A regulates multiple physiological processes including appetite, arousal states, locomotion, hypothalamic-pituitary-adrenal axis activity, and pain perception thresholds. Preclinical studies have demonstrated that intravenous administration of orexin A (3–30 mg/kg) significantly increases paw withdrawal latency in thermal nociception assays, suggestive of analgesic potential. Hence, orexin A serves as a useful tool for investigating neuroendocrine control mechanisms and corresponding therapeutic targets.

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