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Medchemexpress LLC Org 48762-0 50mg | 755753-89-0 | 50 MG
SDP

Supplier:  Medchemexpress LLC HY11422150MG

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Org 48762-0 (UR13870) is a potent, orally active, and selective p38 MAP kinase inhibitor used in research to study inflammatory signaling and cytokine production. It inhibits p38α kinase with low-nanomolar potency in biochemical assays and reduces LPS-induced TNFα release in cellular and animal models.

  • Potent p38α/p38β inhibition (EC50 0.1 μM).
  • Reduces LPS-induced TNFα release in PBMCs (EC50 0.06 μM).
  • Orally bioavailable with demonstrated systemic exposure in mice.
  • High reported purity suitable for biochemical and cellular assays.
  • Stable as a powder at -20°C for long-term storage.

Catalog No. 50-002-27006


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