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Cayman Chemical OrphenadrInhydrochlorIde 50mg

Supplier: Cayman Chemical 2639150 MG

A nucleoside analog inhibits the replication of murine S180 lung carcinoma cells and Ehrlich ascites mammary carcinoma cells (ED50s 8.5 and 4 M respectively) and multiple human leukemia cell lines (IC50s 1.7-5.8 M) acts synergistically with 5-FU against HT-29 HCT116 PANC-1 and EKVX cancer cells inhibits HSV-1 pyrimidine 2-deoxyribonucleoside kinase (Ki 3.5 M) and reduces HSV-1 viral titer to 0.05 of the control at a concentration of 200 M a DNA adduct formed in response to oxidative stress
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