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Rockland Immunochemicals OspB Control Protein 100 µg
SDP

Supplier:  Rockland Immunochemicals 000001C15

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OspB is one of the major Outer Surface Proteins of the outer membrane of Borrelia burgdorferi which is composed of various unique outer surface proteins (Osp) that have been characterized (OspA through OspF). The Osp proteins are lipoproteins anchored by N-terminally attached fatty acid molecules to the membrane. They are presumed to play a role in virulence transmission or survival in the tick. Two of the major surface Ag of Borrelia burgdorferi the 31-kDa OspA and 34-kDa OspB proteins show a high degree of sequence similarity are encoded by a 49-kb plasmid and share a common promoter and are coordinately transcribed. The C terminus of OspB is important for eliciting a protective immune response to OspB. B. burgdorferi has the ability to vary its surface proteins in response to immune attack.

Catalog No. 50-194-3747


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