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Medchemexpress LLC Ots186935 (hydrochloride) | 99.6% | 522.31 | 100 MG
Supplier: Medchemexpress LLC HY122181B100MG
OTS186935 hydrochloride is a potent protein methyltransferase SUV39H2 inhibitor with an IC50 of 6.49 nM. It significantly inhibits tumor growth in mouse xenograft models without detectable toxicity and regulates the production of γ-H2AX in cancer cells. This compound has shown growth suppressive effects in human cancer cell line derived xenograft models.
- Potent SUV39H2 inhibitor
- Inhibits tumor growth in mouse xenograft models
- Regulates production of γ-H2AX in cancer cells
- Shows significant inhibition of tumor growth without detectable toxicity
- Inhibits A549 cell growth with an IC50 of 0.67 μM
- Exhibits growth suppressive effects in human cancer cell line derived xenograft models
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