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ABclonal Technology OXGR1 / GPR99 Rabbit mAb

Supplier: ABclonal Technology A20918100UL
This gene encodes a G protein-coupled receptor (GPCR) that belongs to the oxoglutarate receptor family within the GPCR superfamily The encoded protein is activated by the citric acid intermediate oxoglutarate as well as several cysteinyl leukotrienes including leukotrienes E4 C4 and D4 which are implicated in many inflammatory disorders In mice a knock-out of this gene leads to middle ear inflammation changes in the mucosal epithelium and an increase in fluid behind the eardrum and is associated with hearing loss Alternative splicing results in multiple transcript variants
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