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Medchemexpress LLC Oxidopamine (hydrobromide) | 636-00-0 | 99.4% | 500 MG
Supplier: Medchemexpress LLC HYB1081A500MG
Oxidopamine (6-OHDA) hydrobromide is a potent neurotoxin that selectively destroys dopaminergic neurons by acting as an antagonist of the neurotransmitter dopamine. It is a valuable tool for research into various neurological conditions, including Parkinson's disease (PD), attention-deficit hyperactivity disorder (ADHD), and Lesch-Nyhan syndrome. The compound also promotes COX-2 activation, leading to PGE2 synthesis and pro-inflammatory cytokine IL-1β secretion.
- Selectively destroys dopaminergic neurons
- Antagonist of dopamine neurotransmitter
- Promotes COX-2 activation and PGE2 synthesis
- Induces pro-inflammatory cytokine IL-1β secretion
- Useful for Parkinson's disease research models
- Applicable in ADHD and Lesch-Nyhan syndrome studies
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