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Cayman Chemical OxotremorIn MIodIde 50mg
Supplier: Cayman Chemical 2084750 MG
A muscarinic acetylcholine receptor agonist and KCNQ2/3 potassium channel blocker; induces phosphoinositide hydrolysis in mouse ileum isolated from wild-type, M2, M3 and M2/M3 knockout mice (EC50s = 0.36, 0.52, 1.62, and 1.48 μM, respectively); increases M4-induced inhibition of calcium currents in NG108-15 mouse neuroblastoma X rat glioma hybrid cells (EC50 = 0.14 μM); inhibits KCNQ2/3 potassium currents in Xenopus oocytes expressing M1 receptors and KCNQ2/3 potassium channels (IC50 = 1.1 μM); decreases KCNQ2/3 potassium currents in Xenopus oocytes lacking muscarinic receptors in a dose-dependent manner
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