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Medchemexpress LLC Oxypeucedanin | 737-52-0 | 286.28 | 5 MG
SDP

Catalog No. 5000416347
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Oxypeucedanin is a furanocoumarin derivative found in Angelica dahurica. It acts as an orally active inhibitor of PI3K/AKT/NF-κB, MAPK, and ROS, inducing cell cycle arrest and apoptosis. The compound also inhibits hKv1.5 channel currents and exhibits anticancer, anti-inflammatory, antioxidant, and antiarrhythmic activities.

  • Acts as an orally active inhibitor of PI3K/AKT/NF-κB, MAPK, and ROS.
  • Induces cell cycle arrest and apoptosis.
  • Inhibits hKv1.5 channel currents with an IC50 of 76 nM.
  • Demonstrates anticancer, anti-inflammatory, antioxidant, and antiarrhythmic activities.
  • Inhibits viability of human prostate cancer DU145 cells.
  • Inhibits expression of inflammatory factors and ROS production in RAW264.7 cells.
  • Inhibits lung inflammatory damage in an LPS-induced acute lung injury mouse model.
  • Alleviates severity of collagen-induced arthritis in rats.

Catalog No. 50-004-16347 Supplier Medchemexpress LLC Supplier No. HYN07475MG
May include imposed supplier surcharges.
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Oxypeucedanin is a furanocoumarin derivative found in Angelica dahurica. It acts as an orally active inhibitor of PI3K/AKT/NF-κB, MAPK, and ROS, inducing cell cycle arrest and apoptosis. The compound also inhibits hKv1.5 channel currents and exhibits anticancer, anti-inflammatory, antioxidant, and antiarrhythmic activities.

  • Acts as an orally active inhibitor of PI3K/AKT/NF-κB, MAPK, and ROS.
  • Induces cell cycle arrest and apoptosis.
  • Inhibits hKv1.5 channel currents with an IC50 of 76 nM.
  • Demonstrates anticancer, anti-inflammatory, antioxidant, and antiarrhythmic activities.
  • Inhibits viability of human prostate cancer DU145 cells.
  • Inhibits expression of inflammatory factors and ROS production in RAW264.7 cells.
  • Inhibits lung inflammatory damage in an LPS-induced acute lung injury mouse model.
  • Alleviates severity of collagen-induced arthritis in rats.

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