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Cayman Chemical OxysophocarpIn 50mg
SDP

Supplier:  Cayman Chemical 2830550 MG

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A group I PAK inhibitor (IC50s 8 25 39 5 and 55 3 nM for PAK1 PAK2 and PAK3 respectively) selective for group I PAKs over PAK4 (IC50 779 nM) reverses decreases in the mean density of apical dendritic spines in the temporal cortex in the Fmr1-/- mouse model of fragile X syndrome at 20 mg/kg completely abolishes audiogenic seizures hyperactivity and stereotypical movements in Fmr1-/- mice at 30 mg/kg events adolescent cortical dendritic spine loss and rescues prepulse inhibition deficits in a Disc1 knockdown mouse model of schizophrenia

Catalog No. 50-293-7156


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