Oxytetracycline hydrochloride

Description

Impairs mitochondrial protein synthesis | CAS: 2058-46-0 | C22H25ClN2O9 | 496.897 g/mol

Oxytetracycline is an antibiotic indicated for treatment of infections caused by Gram positive and Gram negative microorganisms such as Mycoplasma pneumoniae, Pasteurella pestis, Escherichia coli, Haemophilus influenzae, and Diplococcus pneumoniae. It is used in studies on the oxytetracycline-resistance gene (otrA). Oxytetracycline hydrochloride is used to study phagosome- lysosome (P-L) fusion in P388D1 cells1 and antibiotic susceptibilities of Mycoplasma bovis isolates.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Oxytetracycline is an antibiotic indicated for treatment of infections caused by Gram positive and Gram negative microorganisms such as Mycoplasma pneumoniae, Pasteurella pestis, Escherichia coli, Haemophilus influenzae, and Diplococcus pneumoniae. It is used in studies on the oxytetracycline-resistance gene (otrA). Oxytetracycline hydrochloride is used to study phagosome- lysosome (P-L) fusion in P388D1 cells1 and antibiotic susceptibilities of Mycoplasma bovis isolates.

Solubility
Soluble in ethanol

Notes
Concentrated aqueous solutions at neutral pH will hydrolyze oxytetracycline and cause it to precipitate

Specifications

Chemical Identifiers

• CAS: 2058-46-0
• Molecular Formula: C22H25ClN2O9
• Molecular Weight (g/mol): 496.897
• MDL Number: MFCD00135815
• InChI Key: UTAHTGPLLFLKGW-IFLJXUKPSA-N
• PubChem CID: 121235537
• IUPAC Name: (4S,4aR,5S,5aR,6S,12aS)-4-(dimethylamino)-3,5,6,10,11,12a-hexahydroxy-6-methyl-1,12-dioxo-4,4a,5,5a-tetrahydrotetracene-2-carboxamide;hydrochloride
• SMILES: CC1(C2C(C3C(C(=C(C(=O)C3(C(=O)C2=C(C4=C1C=CC=C4O)O)O)C(=O)N)O)N(C)C)O)O.Cl

• Type: Oxytetracycline Hydrochloride
• Physical Form: Crystalline Powder
• Melting Point: 180°C
• Color: Gray to Yellow
• Quantity: 25 g
• Sensitivity: Air and light sensitive
• Beilstein: 3853107
• Merck Index: 14,6976
• Solubility Information: Soluble in ethanol
• Formula Weight: 496.9
• Chemical Name or Material: Oxytetracycline hydrochloride

Safety and Handling

Hazard Category	H319-H361d
Precautionary Statement	P201-P202-P264b-P280i-P281-P305+P351+P338-P308+P313-P501c
EINECSNumber	218-161-2
RTECSNumber	QI8225000
TSCA	Yes
Recommended Storage	Ambient temperatures; Store under Argon

SDS

RUO – Research Use Only