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Medchemexpress LLC Ozagrel (hydrochloride) | 78712-43-3 | MFCD00911569 | 99.9% | 1 ML
SDP

Catalog No. 5000409166
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Ozagrel hydrochloride is a highly selective and orally active thromboxane A2 (TXA2) synthase inhibitor with an IC50 of 11 nM. It achieves anti-platelet aggregation, vasodilation, and anti-inflammatory effects by inhibiting TXA2 production and increasing prostacyclin (PGI2) production. This compound is used for the study of ischemic stroke, asthma, and thromboembolic diseases.

  • IC50 of 11 nM for TXA2/TP.
  • Significantly inhibits platelet aggregation (IC50 53.12 μM) induced by arachidonic acid.
  • Improves endothelial dysfunction, oxidative stress, and neuroinflammation in rat models.
  • Attenuates lung injury and decreases monocyte chemoattractant protein-1 and interleukin-8 mRNA expression.
  • Documentation includes data sheet, COA, SDS, and handling instructions.

Catalog No. 50-004-09166 Supplier Medchemexpress LLC Supplier No. HYB0428B10MM/1ML
May include imposed supplier surcharges.
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Ozagrel hydrochloride is a highly selective and orally active thromboxane A2 (TXA2) synthase inhibitor with an IC50 of 11 nM. It achieves anti-platelet aggregation, vasodilation, and anti-inflammatory effects by inhibiting TXA2 production and increasing prostacyclin (PGI2) production. This compound is used for the study of ischemic stroke, asthma, and thromboembolic diseases.

  • IC50 of 11 nM for TXA2/TP.
  • Significantly inhibits platelet aggregation (IC50 53.12 μM) induced by arachidonic acid.
  • Improves endothelial dysfunction, oxidative stress, and neuroinflammation in rat models.
  • Attenuates lung injury and decreases monocyte chemoattractant protein-1 and interleukin-8 mRNA expression.
  • Documentation includes data sheet, COA, SDS, and handling instructions.

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