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ABclonal Technology p-AMPKa1-T183-AMPKa2-T172
Supplier: ABclonal Technology AP144120UL
The protein encoded by this gene belongs to the ser thr protein kinase family It is the catalytic subunit of the 5 -prime-AMP-activated protein kinase (AMPK) AMPK is a cellular energy sensor conserved in all eukaryotic cells The kinase activity of AMPK is activated by the stimuli that increase the cellular AMP ATP ratio AMPK regulates the activities of a number of key metabolic enzymes through phosphorylation It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways Alternatively spliced transcript variants encoding distinct isoforms have been observed
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