Invitrogen™ Human P-cadherin (CDH3) ELISA Kit

Catalog No.	Quantity
EHCDH3X10	10 x 96 Tests

Catalog No. EHCDH3X10 Supplier Invitrogen™ Supplier No. EHCDH3X10

Description

ELISA

P-cadherin, also known as Cadherin-3, is a Type 1 cadherin protein that belongs to the cadherin superfamily. Type 1 cadherins are single-pass transmembrane proteins that have 5 extracellular cadherin repeats and an intracellular domain that binds p120-catenin and beta-catenin. Cadherins are calcium-dependent cell-cell adhesion glycoproteins responsible for a range of processes including development, wound healing, cell-cell signaling, cell growth and differentiation. P-cadherin is expressed in human fetal structures, and in adult tissues such as the basal layer of the epidermis, breast, prostate, ovary, cervix, hair follicle, and corneal endothelium. P-cadherin expression has also been reported on embryonic stem cells, and stem cells of the normal mammary gland, and hair follicle. Overexpression of P-cadherin has been associated with poor prognosis in breast, prostate, ovary, colon, and stomach carcinomas. Mutations in CDH3 are associated with congential hypotrichosis with juvenile macular dystrophy.

Specifications

• Accession Number: P22223
• Assay Range: 2.47 to 18,000 pg/mL
• Assay Sensitivity: 20 pg/mL
• Conjugate: HRP
• Product Type: ELISA
• Sample Type: Plasma, Serum, Supernatant
• For Use With (Equipment): Colorimetric Microplate Reader
• Gene ID (Entrez): 1001
• Gene Symbol: Cdh3
• Interassay CV: <12%
• Intraassay CV: <10
• Kit Contents: Pre-coated 96 well plate, Standard, Assay Diluent concentrate, Biotinylated Detection Antibody, SAV-HRP, Wash Buffer, Chromogen, Stop Solution, Adhesive Plate Covers
• Label or Dye: HRP
• Quantity: 10 x 96 Tests
• Regulatory Status: RUO
• Sample Volume: Plasma 3.3 μL, Serum 3.3 μL, Supernatant 100 μL
• Storage Requirements: 2°C to 8°C
• Target: P-cadherin
• Test Time: 1 hrs 20 mins
• Total Assay Time: 4 hrs 45 mins