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Medchemexpress LLC p-Cresyl sulfate | 3233-58-7 | 99.98% | 188.20 | 25 MG
Supplier: Medchemexpress LLC 25MGHY111431AR
p-Cresyl sulfate (p-Tolyl sulfate) is a uremic toxin that can cause renal damage and dysfunction. It demonstrates antiproliferation activity, increases the protein expression of HIF-1α and VHL, and decreases the protein expression of HIF-2α. Additionally, p-Cresyl sulfate induces epithelial-mesenchymal transition (EMT) and activates the JNK and p38 MAPK signaling pathways.
- Is a uremic toxin.
- Can cause renal damage and dysfunction.
- Shows antiproliferation activity.
- Increases the protein expression of HIF-1α and VHL.
- Decreases the protein expression of HIF-2α.
- Induces epithelial-mesenchymal transition (EMT).
- Activates the JNK and p38 MAPK signaling pathways.
- Inhibits lipogenesis and increases lipolysis in adipocytes in 3T3-L1 cells.
- Induces osteoblast dysfunction through activating JNK and p38 MAPK pathways.
- Induces ROS production in primary osteoblastic cells.
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