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ABclonal Technology p-cTnl TNNI3-S23/S24
Supplier: ABclonal Technology AP1400100UL
Troponin I (TnI) along with TnT and TnC forms the troponin complex of thin filaments in striated muscle TnI acts as the inhibitory subunit blocking actin-myosin interactions and mediating muscle relaxation The TnI subfamily includes TnI-skeletal-fast-twitch TnI-skeletal-slow-twitch and TnI-cardiac This gene encodes the cardiac TnI protein which is exclusively expressed in cardiac muscle Mutations cause familial hypertrophic cardiomyopathy type 7 (CMH7) and familial restrictive cardiomyopathy (RCM) TnI is used to diagnose heart failure and ischemic heart disease Elevated troponin levels are indicators of acute myocardial injury in patients with moderate-to-severe COVID-19 and are associated with higher mortality risk in cardiovascular disease patients hospitalized with COVID-19
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