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ABclonal Technology p-HDAC4/5/9-S246/S259/S220
Supplier: ABclonal Technology AP139420UL
Histones play a critical role in transcriptional regulation cell cycle progression and developmental events Histone acetylation deacetylation alters chromosome structure and affects transcription factor access to DNA The protein encoded by this gene belongs to class II of the histone deacetylase acuc apha family It possesses histone deacetylase activity and represses transcription when tethered to a promoter This protein does not bind DNA directly but through transcription factors MEF2C and MEF2D It seems to interact in a multiprotein complex with RbAp48 and HDAC3 [provided by RefSeq Jul 2008]
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