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ABclonal Technology p-PLC gamma 2 PLCG2-Y759
SDP

Supplier:  ABclonal Technology AP1519100UL

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The protein encoded by this gene is a transmembrane signaling enzyme that catalyzes the conversion of 1-phosphatidyl-1D-myo-inositol 4 5-bisphosphate to 1D-myo-inositol 1 4 5-trisphosphate (IP3) and diacylglycerol (DAG) using calcium as a cofactor IP3 and DAG are second messenger molecules important for transmitting signals from growth factor receptors and immune system receptors across the cell membrane Mutations in this gene have been found in autoinflammation antibody deficiency and immune dysregulation syndrome and familial cold autoinflammatory syndrome 3

Catalog No. 50-000-13713


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