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Medchemexpress LLC p-Tolylmaleimide | 1631-28-3 | 98.0% | 100 MG
SDP

Supplier:  Medchemexpress LLC HY129592100MG

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p-Tolylmaleimide (compound 9) is a naphthalimide derivative with cytotoxic effects on cancer cells. It can arrest the cell cycle of human acute myeloid leukemia cells K562 in the sub-G0/G1 phase and induce apoptosis.

  • Inhibits human acute myeloid leukemia cell K562 with IC50s of 24.99 μM (24 h), 6.61 μM (48 h), and 12.10 μM (72 h).
  • Inhibits human acute myeloid leukemia cell Jurkat with IC50s of 27.16 μM (24 h), 15.51 μM (48 h), and 3.94 μM (72 h).
  • Cytotoxicity against human MCF7, NCI-H460, and SF-268 cells (GI50 > 10 μg/mL).

Catalog No. 50-003-41265


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